An eHealth Android Application for Mobile Analysis of Microplate Assays

Bellairs, James and Hlozek, Jason and Egan, Timothy and Kuttel, Michelle (2016) An eHealth Android Application for Mobile Analysis of Microplate Assays, Proceedings of IST-Africa 2016, 11-13 June 2016, Durban, South Africa, IEEE Xplore.

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Drug efficacy assays with microplate readers are a key aspect of the modern drug discovery process. However, microtitre plate readers are expensive laboratory equipment and not easily transportable. We have created a prototype Android smartphone application that enables smartphones to measure the concentration values in microplate wells. We find that the smartphone camera measures concentrations of red and yellow solutions more accurately than green. Further, concentration readings are most accurate when microplates are backlit and sources of noise (such as glare and shadows) are removed. Therefore, we designed a simple dark box to control ambient light, which reduces the error in measurements to within 7% of a laboratory microplate reader. An affordable and mobile alternative to a microplate reader is expected to support drug research in developing countries by enabling rapid, cheap drug assays in small laboratories and in field work with a standard Android smartphone.

Item Type: Conference paper
Uncontrolled Keywords: Android, eHealth, mobile, infectious disease, Colourimetric assay, Smartphone, Plate Reader, microplate
Subjects: Software and its engineering > Software creation and management
Computing methodologies > Computer graphics > Image manipulation > Image processing
Applied computing > Physical sciences and engineering
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Date Deposited: 18 Nov 2016
Last Modified: 10 Oct 2019 15:32

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